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HERPES VIRUS MAY CAUSE MULTIPLE SCLEROSIS

Increasing evidence from peripheral blood cultures in autopsy studies suggests that reactivation of human herpes virus-6 infection appears to play a central role in the pathogenesis of multiple sclerosis. Control of III IV-6 infection with an anti-viral agent such as ganciclovir may alter the course of the disease, reported Dr. Joseph Brewer at the annual meeting of the Infection Diseases Society in Denver.

Ht IV-6 infection, the cause of a variety Of illnesses, including roseola, is a com- coon pathogen acquired by most individuals by 3 years of age. HIV-6 viremia was found in 8 out of 13 patients with relapsing, remitting MS and 6 of 12 patients with chronic progressive MS. So far, Dr. Brewer has found active HI IV-6 infection in CNS tissue taken from 8 of 11 MS patients. When these infected cells were found, they were always located in MS lesion or plaques. I le has treated 5 MS patients with IV Gancilovir, with the longest follow up being 11 months. The antiviral agent appears to control MS symptoms and prevent relapses, but further studies are needed to confirm this.

OB GYN News, tan. 99

 



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